| Cat # | Size | Price | Quantity | |
|---|---|---|---|---|
| 100401 | 100 ug | $50 | ||
| 100402 | 500 ug | $150 |
| Clone | 011bAB |
|---|---|
| Application | FC |
| Reactivity | Human |
| Format | Purified |
| Target Name | CD11b, Integrin αM chain, C3biR, CR3, Mac-1, Mo1, ITGAM |
| Isotype | Rabbit IgG |
| Antibody Type | Monoclonal |
| Regulatory Status | RUO |
| Formulation | Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide |
| Protein Concentration | 0.5 mg/mL |
| Storage and Handling | The antibody solution should be stored between 2°C and 8°C |
| Recommended Usage | For flow cytometric staining, it is recommended to use less than 0.2 ug of this reagent per 0.5-1.0 million cells in a 100 µL volume. Optimal reagent performance should be determined by titration for each specific application |
Integrin Alpha M (ITGAM); the alpha subunit of Mac-1 (Macrophage-1 antigen), the CR3 complement receptor which consists of CD11b and CD18. CR3 is a human cell surface receptor, found on polymorphonuclear leukocytes (mostly neutrophils), NK cells, and mononuclear phagocytes like macrophages, which is capable of recognizing and binding to many molecules found on the surfaces of invading bacteria. Binding to the receptor causes phagocytosis and destruction of the foreign cell.
