| Cat # | Size | Price | Quantity | |
|---|---|---|---|---|
| 202201 | 100 ug | $45 | ||
| 202202 | 500 ug | $100 |
| Clone | 30-F11 |
|---|---|
| Application | FC |
| Reactivity | Human, Mouse |
| Format | Purified |
| Target Name | CD45, Ly-5, LCA, T200 |
| Isotype | Rab IgG2b |
| Antibody Type | Monoclonal |
| Regulatory Status | RUO |
| Formulation | Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide |
| Protein Concentration | 0.5 mg/mL |
| Storage&Handling | The antibody solution should be stored between 2°C and 8°C |
| Recommended Usage | For flow cytometric staining, it is recommended to use less than 0.2 ug of this reagent per 0.5-1.0 million cells in a 100 µL volume. Optimal reagent performance should be determined by titration for each specific application. |
CD45 is a receptor-type protein tyrosine phosphatase expressed on the plasma membrane of all nucleated hematopoietic cells, excluding erythrocytes and platelets. It is a critical signaling molecule regulating immune cell activation, growth, differentiation, cell cycle, and oncogenic transformation. CD45 constitutes a large proportion of lymphocyte surface proteins (~10%) and is essential for T- and B-cell receptor-mediated activation.
