| Cat # | Size | Price | Quantity | |
|---|---|---|---|---|
| 202207 | 25 tests | $28 | ||
| 202208 | 100 tests | $75 |
| Clone | 30-F11 |
|---|---|
| Application | FC |
| Reactivity | Mouse |
| Format | APC |
| Target Name | CD45, Ly-5, LCA, T200 |
| Isotype | Rat IgG2b |
| Antibody Type | Monoclonal |
| Regulatory Status | RUO |
| Formulation | Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and 0.2% (w/v) BSA |
| Protein Concentration | Supplied at a lot-specific concentration. |
| Storage&Handling | The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze. |
| Recommended Usage | For flow cytometric staining, it is recommended to use 5 uL of this reagent per 0.5-1.0 million cells in a 100 µL volume. Optimal reagent performance should be determined by titration for each specific application. |
| Excitation Laser | Red Laser (633 nm) |
CD45 is a receptor-type protein tyrosine phosphatase expressed on the plasma membrane of all nucleated hematopoietic cells, excluding erythrocytes and platelets. It is a critical signaling molecule regulating immune cell activation, growth, differentiation, cell cycle, and oncogenic transformation. CD45 constitutes a large proportion of lymphocyte surface proteins (~10%) and is essential for T- and B-cell receptor-mediated activation.
