| Cat # | Size | Price | Quantity | |
|---|---|---|---|---|
| 605101 | 25 ug | $145 | ||
| 605102 | 100 ug | $295 |
| Application | ELISA, BLI |
|---|---|
| Format | Liquid, Purified |
| Expression Host | HEK293 |
| Target Name | OX40L, TNFSF4, CD252, TXGP1, CD134 ligand, , Glycoprotein Gp34 |
| Species | Cynomolgus monkey |
| Accession Number | A0A2K5TTN0 |
| Sources | Recombinant Cynomolgus Monkey OX40L (Gln51-Leu183) with N-terminus Fc tag is expressed in 293 cells |
| Molecular Weight | This protein has a predicted molecular weight of 41.4 kDa. Under DTT-reducing conditions, the protein migrates at approximately 50 kDa on SDS-PAGE. |
| Affinity Tag | N-Fc |
| Purity | >95% based on SDS-PAGE under reducing condition |
| Regulatory Status | RUO |
| Formulation | 1xPBS buffer, pH7.4, 0.22 µm filtered |
| Endotoxin level | Not tested |
| Protein Concentration | 25µg size is bottled at 0.2mg/mL concentration. 100 µg size is supplied at a lot-specific concentration. |
| Storage and Handling | Briefly centrifuge the vial upon receipt. An unopened vial can be stored at 4°C for up to 2 weeks, or at -20°C or below for up to six months. The protein may be further diluted to 0.1 mg/mL using 0.22 µm-filtered PBS buffer (pH 7.4). For long-term storage, the diluted stock solution should be aliquoted and stored at ≤ –70°C to minimize freeze-thaw cycles. If additional dilution is required, carrier proteins such as FBS or BSA should be added to maintain protein stability. |
OX40 ligand (also known as CD252) is a member of the tumor necrosis factor (TNF) superfamily and serves as the natural ligand for the costimulatory receptor OX40 (CD134) on T cells. Expressed primarily on antigen-presenting cells such as B cells’ dendritic cells, OX40L plays a key role in regulating immune responses by promoting T cell activation, proliferation, survival, and memory formation. The interaction between OX40L and OX40 is critical for sustaining effective adaptive immunity and is a promising target in therapies for cancer, autoimmune diseases, and chronic inflammation.
