| Cat # | Size | Price | Quantity | |
|---|---|---|---|---|
| 101303 | 25 tests | $80 | ||
| 101304 | 100 tests | $220 |
| Clone | 020AR1 |
|---|---|
| Application | FC |
| Reactivity | Human |
| Format | iF488 |
| Target Name | CD20, MS4A-1 |
| Isotype | Rat IgG1 |
| Antibody Type | Monoclonal |
| Regulatory Status | RUO |
| Formulation | Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and 0.2% (w/v) BSA |
| Protein Concentration | Supplied at a lot-specific concentration. |
| Storage and Handling | The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze. |
| Recommended Usage | For flow cytometric staining, it is recommended to use 5 uL of this reagent per 0.5-1.0 million cells in a 100 µL volume. Optimal reagent performance should be determined by titration for each specific application. |
| Excitation Laser | Blue Laser (488 nm) |
B-lymphocyte antigen CD20 or CD20 is expressed on the surface of all B-cells beginning at the pro-B phase (CD45R+, CD117+) and progressively increasing in concentration until maturity. expressed in B-cell lymphomas, hairy cell leukemia, and B-cell chronic lymphocytic leukemia. The protein has no known natural ligand[9] and its function is to enable optimal B-cell immune response, specifically against T-independent antigens.[10] It is suspected that it acts as a calcium channel in the cell membrane. CD20 has been linked to the signaling propensity of B-cell receptor (BCR).
