| Cat # | Size | Price | Quantity | |
|---|---|---|---|---|
| 109805 | 25 tests | $95 | ||
| 109806 | 100 tests | $230 |
| Clone | IV.3 |
|---|---|
| Application | FC |
| Reactivity | Human |
| Format | iF488 |
| Target Name | CD32, FcγRII, FCRII |
| Isotype | Mouse IgG2b |
| Antibody Type | Monoclonal |
| Regulatory Status | RUO |
| Formulation | Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and 0.2% (w/v) BSA |
| Protein Concentration | Supplied at a lot-specific concentration. |
| Storage&Handling | The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze. |
| Recommended Usage | For flow cytometric staining, it is recommended to use 5 uL of this reagent per 0.5-1.0 million cells in a 100 µL volume. Optimal reagent performance should be determined by titration for each specific application. |
| Excitation Laser | Blue Laser (488 nm) |
CD32 is a ~40-kDa polymorphic transmembrane glycoprotein belonging to the immunoglobulin superfamily. Also known as FcγRII or FCRII, it is expressed on a wide variety of immune and blood cells including B cells, monocytes/macrophages, granulocytes, platelets, and it has also been detected on natural killer (NK) cells. There are multiple isoforms of CD32 (at least six produced by alternative mRNA splicing). In humans, the major functional subtypes are CD32A and CD32C (activating) and CD32B (inhibitory).