| Cat # | Size | Price | Quantity | |
|---|---|---|---|---|
| 800001 | 25 ug | $145 | ||
| 800002 | 100 ug | $295 |
| Application | ELISA, BLI |
|---|---|
| Format | Liquid, Purified |
| Expression Host | HEK293 |
| Target Name | CD38, T10, cADPr 1 |
| Species | Human |
| Sources | Human CD38 protein (Val43-Ile300) with C-terminus His tag and Avi tag is expressed in HEK293 cells. |
| Accession Number | P28907 |
| Molecular Weight | The 285 amino acid protein has a predicted molecular weight of 33 kDa. The protein migrates at approximately 35-45 kDa on SDS-PAGE with DTT-reduced conditions. |
| Affinity Tag | C-His-Avi |
| Purity | >95% based on SDS-PAGE under reducing condition |
| Regulatory Status | RUO |
| Formulation | 1xPBS buffer, pH7.4, 0.22 µm filtered |
| Endotoxin level | Not tested |
| Protein Concentration | 25µg size is bottled at 0.2mg/mL concentration. 100 µg size is supplied at a lot-specific concentration. |
| Storage and Handling | Briefly centrifuge the vial upon receipt. An unopened vial can be stored at 4°C for up to 2 weeks, or at -20°C or below for up to six months. The protein may be further diluted to 0.1 mg/mL using 0.22 µm-filtered PBS buffer (pH 7.4). For long-term storage, the diluted stock solution should be aliquoted and stored at ≤ –70°C to minimize freeze-thaw cycles. If additional dilution is required, carrier proteins such as FBS or BSA should be added to maintain protein stability. |
CD38 (ADP-ribosyl cyclase 1) is a Type II membrane protein involved in calcium signaling through the conversion of NAD(P)+ into cADPR, NAADP+, and ADP-ribose. It is broadly expressed in immune cells and various tissues, and is linked to immune regulation, cancer, and metabolic disorders. CD38 also serves as a prognostic marker in leukemia.
