Andes Virus Glycoprotein Gn Head (C-His)

Cat #	Size	Price	Quantity
606801	25 μg	$300
606802	100 μg	$785

Bulk/Custom

Product Details

Application	ELISA, BLI
Format	Liquid, Purified
Expression Host	CHO
Target Name	Andes virus glycoprotein Gn Head, Andes virus Gn protein, ANDV Gn glycoprotein, Andes orthohantavirus glycoprotein Gn, Hantavirus envelope glycoprotein Gn, G1 glycoprotein
Species	Andes Virus
accession number	AF291703.2
Sources	Recombinant Andes Virus Glycoprotein Gn Head (Met19–Glu374) with a C-terminal histidine tag is expressed in CHO cells. The protein is derived from the Andes virus strain Chile-9717869.
Molecular Weight	This protein has a predicted molecular weight of 39–41 kDa (without glycosylation).
Affinity Tag	C-His
Purity	>95% based on SDS-PAGE under reducing condition
Regulatory Status	RUO
Formulation	1xPBS buffer, pH7.4, 0.22 µm filtered
Endotoxin level	Not tested
Protein Concentration	25µg size is bottled at 0.2mg/mL concentration. 100 µg size is supplied at a lot-specific concentration.
Storage and Handling	Briefly centrifuge the vial upon receipt. An unopened vial can be stored at 4°C for up to 2 weeks, or at -20°C or below for up to six months. The protein may be further diluted to 0.1 mg/mL using 0.22 µm-filtered PBS buffer (pH 7.4). For long-term storage, the diluted stock solution should be aliquoted and stored at ≤ –70°C to minimize freeze-thaw cycles. If additional dilution is required, carrier proteins such as FBS or BSA should be added to maintain protein stability.

Background Information

Andes virus (ANDV) is an enveloped negative-sense RNA virus belonging to the genus Orthohantavirus within the family Hantaviridae. Andes virus is one of the major causative agents of hantavirus cardiopulmonary syndrome (HCPS) in South America and is notable for its documented human-to-human transmission capability.
The viral surface glycoprotein precursor (GPC) is proteolytically processed into the Gn and Gc envelope glycoproteins, which mediate viral attachment, host-cell entry, membrane fusion, and immune recognition. The Gn head domain is highly exposed on the virion surface and serves as a major target for neutralizing antibodies. Recombinant Andes Virus Gn Head Protein is widely used in antiviral antibody discovery, vaccine research, serological assay development, epitope mapping, and structural biology studies.

Learn more about Andes Virus in our detailed Infographic.

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